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CAS RN: 179688-29-0 | Product Number: B4270
6,7-Bis(2-methoxyethoxy)-3H-quinazolin-4-one
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone
- 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one
- 6,7-Bis(2-methoxyethoxy)-4-hydroxyquinazoline
- 6,7-Bis(2-methoxyethoxy)-4-quinazolinol
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
¥3,000
|
It can be shipped in about 2-3 business days after ordering | 2 | Contact Us | |
| 5G |
¥11,400
|
1 | 2 | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | B4270 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__8N__2O__5 = 294.31 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 179688-29-0 |
| Reaxys Registry Number | 10087641 |
| PubChem Substance ID | 253660263 |
| MDL Number | MFCD02678087 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 190.0 to 194.0 °C |
Properties (reference)
| Melting Point | 192 °C |
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Application
A Key Synthetic Intermediate of Erlotinib
This product is a key synthetic intermediate of erlotinib which is a receptor tyrosine kinase inhibitor acting on the epidermal growth factor receptor (EGFR), such as gefitinib [G0546].
References
- Improved synthesis of substituted 6,7-dihydroxy-4-quinazolineamines: tandutinib, erlotinib and gefitinib
- Improved Synthesis of Gefitinib and Erlotinib Hydrochloride-Anticancer Agents
- Modified Synthesis of Erlotinib Hydrochloride
- Separation and determination of process-related impurities of erlotinib using reverse-phase HPLC with a photo-diode array detector
PubMed Literature
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