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Published TCIMAIL newest issue No.197
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CAS RN: 152-95-4 | Product Number: S0835
Sophoricoside
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Purity: >98.0%(HPLC)
Synonyms:
- Genistein 4'-Glucoside
- 4'-(β-D-Glucopyranosyloxy)-5,7-dihydroxyisoflavone
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 100MG |
€146.00
|
Contact Us | 2 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | S0835 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__0O__1__0 = 432.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 152-95-4 |
| Reaxys Registry Number | 63197 |
| PubChem Substance ID | 125307426 |
| MDL Number | MFCD01075138 |
Specifications
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | -17.0 to -22.0 deg(C=1, Pyridine) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 297 °C |
| Specific Rotation | -18° (C=1,Pyridine) |
| Maximum Absorption Wavelength | 271(MeOH) nm |
GHS
Related Laws:
Transport Information:
| HS Number | 2938909090 |
Application
Sophoricoside: An Isoflavone Glycoside with Inhibitory Effects of IL-5, IL-3, IL-6, and COX-2 Activities
Sophoricoside is an isoflavone glycoside found in Sophora japonica L. (Leguminosae family) which is a traditional Chinese medicinal herb used as hemostatic agent.1) Pharmacological studies have demonstrated that Sophora japonica L. has antitumor and antifertility activities.1) It has been reported that sophoricoside exhibits inhibitory effects on interleukin-5 (IL-5), IL-3, IL-6, and COX-2 activities.2-5) (The product is for research purpose only.)
References
- 1) Determination of sophoricoside in rat plasma by HPLC and its application to pharmacokinetic studies
- 2) Sophoricoside analogs as the IL-5 inhibitors from Sophora japonica
- 3) Differential inhibitory effects of sophoricoside analogs on bioactivity of several cytokines
- 4) Anti-inflammatory mode of isoflavone glycoside sophoricoside by inhibition of interleukin-6 and cyclooxygenase-2 in inflammatory response
- 5) Anti-inflammatory action of legume isoflavonoid sophoricoside through inhibition on cyclooxygenase-2 activity
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