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Published TCIMAIL newest issue No.197
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CAS RN: 59-67-6 | Product Number: N0082
Nicotinic Acid
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Purity: >99.0%(T)(HPLC)
Synonyms:
- Niacin
- Pyridine-3-carboxylic Acid
- Vitamin B3
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25G |
€16.00
|
16 | ≥100 |
|
| 500G |
€37.00
|
5 | ≥80 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | N0082 |
| Purity / Analysis Method | >99.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__6H__5NO__2 = 123.11 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 59-67-6 |
| Reaxys Registry Number | 109591 |
| PubChem Substance ID | 87573475 |
| SDBS (AIST Spectral DB) | 7944 |
| Merck Index (14) | 6525 |
| MDL Number | MFCD00006391 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 99.0 area% |
| Purity(Neutralization titration) | min. 99.0 % |
| Melting point | 235.0 to 240.0 °C |
| Solubility in hot Water | almost transparency |
Properties (reference)
| Melting Point | 238 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 200-441-0 |
| RTECS# | QT0525000 |
Transport Information:
| HS Number | 2936290000 |
Application
ニコチン酸の三つの面：ビタミンB3，抗高脂血症剤，および配位高分子化合物の架橋リガンド
Nicotinic acid has three faces. The first is vitamin B3 (called niacin) which is required for the synthesis of coenzymes, nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP).1) The second is an antilipemic agent which acts on the nicotinic acid receptor, inhibiting the enzyme triglyceride lipase.2-4) The last is a bridging ligand for coordination polymers which is used for the synthesis of MOF/PCP.5) For your reference, we have its analogue, acipimox [M2053]. (The product is for research purpose only.)
References
- 1)Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition (a review)
- 2)Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review
- 3)Mechanism of action of niacin
- 4)Nicotinic acid: pharmacological effects and mechanisms of action (a review)
- 5)Novel 3-D Framework Nickel(II) Complex with Azide, Nicotinic Acid, and Nicotinate(1-) as Coligands: Hydrothermal Synthesis, Structure, and Magnetic Properties
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Related Products
![Nicotinic Acid [Matrix for MALDI-TOF/MS]](/medias/N1103.jpg?context=bWFzdGVyfHJvb3R8MzIyMDB8aW1hZ2UvanBlZ3xhRGRoTDJoa05pODRPVE14TnpRNU56STBNVGt3TDA0eE1UQXpMbXB3Wnd8NDAxYjhhNTQ2ZmJjNTMxYTRlNTc4OGYzODViZTI0MmYyNDNmMGY5MjI5NjdhZDIzZDUzZGQ0ZGEyNjY2MDc3Zg "Nicotinic Acid [Matrix for MALDI-TOF/MS]")
Nicotinic Acid [Matrix for MALDI-TOF/MS]
| Product # | N1103 |
| CAS RN | 59-67-6 |
| Purity / Analysis Method: | >99.5%(T)(HPLC) |