Caution Notice:
It has come to our notice that certain fraudulent individuals or entities are misusing our Company’s name and TCI’s registered trademarks by promoting and offering for sale regulated and hazardous chemical substances, including Potassium Cyanide, through online platforms like YouTube. We hereby categorically clarify that TCI has no association or connection whatsoever with the products being displayed or sold in these or similar videos. These products have been falsely represented as being associated with TCI, and the unauthorized use of our trademark and brand name is both illegal and misleading. TCI Chemicals is a responsible global organization committed to adhering to all applicable international and domestic regulatory frameworks. We do not manufacture, distribute, or engage in the sale of regulated chemical substances in India or in any other jurisdiction unless specifically authorized by the relevant laws and regulatory agencies. All our operations and offerings are governed by stringent safety, quality, and compliance protocols in accordance with applicable laws. Further, TCI Chemicals markets and sells its products exclusively through its official website and authorized distributors. We do not sell, endorse, or supply our products through any third-party platforms, unauthorized agents, or resellers. Any individual or organization purchasing products outside these official channels does so at their own risk, and TCI disclaims all responsibility and liability for any consequences arising therefrom. Members of the public, customers, and partners are strongly advised to exercise caution and conduct due diligence before engaging in any transactions involving products claiming association with TCI Chemicals. The official list of our authorized distributors is publicly available and may be accessed at: https://www.tcichemicals.com/IN/en/distributor/index. We are currently pursuing appropriate legal remedies against those misusing our brand, and we reserve all rights available to us under applicable intellectual property and criminal laws. If you become aware of any such fraudulent activity or require clarification, you may reach out to us at: Sales-IN@TCIchemicals.com. Your vigilance and cooperation are essential in safeguarding the public interest and protecting the integrity of the TCI brand.
Maximum quantity allowed is 999
Modulators of the ERK Signaling Pathway
- L0470
- SL 327 [Optimized for Cell Culture] (1)
- P3159
- PD 98059 [Optimized for Cell Culture] (2)
- P3157
- PD 184352 [Optimized for Cell Culture] (3)
- O0672
- Sorafenib [Optimized for Cell Culture] (4)
- G0649
- GW 5074 [Optimized for Cell Culture] (5)
- F1381
- FR 180204 [Optimized for Cell Culture] (6)
- I1257
- Insulin solution (4mg/mL) [Optimized for Cell Culture] (7)
- R0262
- rhEGF (Human, Recombinant) (100µg/vial) (8)
Extracellular signal-Regulated Kinase (ERK), a member of the mitogen-activated protein kinase (MAPK) family, plays a crucial role in regulating cell growth, proliferation, and differentiation. Dysregulation of the ERK pathway has been implicated in various diseases, including cancer.1-3)
Modulation of the ERK signaling pathway is known to regulate various biological processes which play roles in cellular behavior. The most common commercial inhibitors of the ERK signaling pathway are the various small molecule kinase inhibitors listed above (1-6). Additionally, TCI also offers several common activators of the ERK pathway including insulin (7), and EGF (8). TCI offers the majority of these modulators at a special [Optimized for Cell Culture] grade.

About [Optimized for Cell Culture]
The [Optimized for Cell Culture] series comprises products that have undergone mycoplasma and endotoxin testing, ensuring their safety for use in cell biology research. These products are ideal for various applications, including disease modeling and regenerative medicine research.
References
- 1) RAF-MEK-ERK pathway in cancer evolution and treatment
- 2) Insulin Stimulates Mitogen-activated Protein Kinase by a Ras-independent Pathway in 3T3-L1 Adipocytes
- 3) Non-canonical integrin signaling activates EGFR and RAS-MAPK-ERK signaling in small cell lung cancer
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