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CAS RN: 131543-23-2 | Product Number: W0019
WIN 55212-2 Mesylate
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Purity: >98.0%(HPLC)
Synonyms:
- (R)-(5-Methyl-3-(morpholinomethyl)-2,3-dihydro-[1,4]oxazino[2,3,4-hi]indol-6-yl)(naphthalen-1-yl)methanone Methanesulfonate
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 50MG |
₹18,500.00
|
Contact Us | 2 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | W0019 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__7H__2__6N__2O__3·CH__4O__3S = 522.62 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| CAS RN | 131543-23-2 |
| Reaxys Registry Number | 4903069 |
| MDL Number | MFCD00153882 |
Specifications
| Appearance | White to Light gray to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 238.0 to 242.0 °C |
| Specific rotation | +39.0 to +43.0 deg(C=1, DMF) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 240 °C |
GHS
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Application
WIN 55212-2 Mesylate: A High Affinity Cannabinoid Receptor Agonist
WIN 55212-2 mesylate is a high affinity cannabinoid (CB) receptor agonist. It is known that CB receptors inhibit the release of various transmitters such as glutamate, GABA, and acetylcholine (ACh) through endogenous cannabinoids that are present in the presynaptic membrane and released from the postsynaptic membrane. Therefore, the activation of CB receptors by WIN 55212-2 have recently studied as a possible treatment of stress- and anxiety- related disorders. (The product is for research purpose only.)
References
- The analgesic effects of R(+)-WIN 55,212-2 mesylate, a high affinity cannabinoid agonist, in a rat model of neuropathic pain
- Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures
- Cannabinoids Prevent the Development of Behavioral and Endocrine Alterations in a Rat Model of Intense Stress
- Moving around the molecule: Relationship between chemical structure and in vivo activity of synthetic cannabinoids (a review)
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