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CAS RN: 212142-18-2 | Product Number: V0198
Vatalanib Succinate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- N-(4-Chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine Succinate
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
₹13,800.00
|
Contact Us | 20 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | V0198 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__1__5ClN__4·C__4H__6O__4 = 464.91 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 212142-18-2 |
| Reaxys Registry Number | 14123653 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
Application
Vatalanib Succinate: A Specific Inhibitor of VEGF Receptor Tyrosine Kinases
Vascular endothelial growth factor (VEGF) is one of the major factors involved in tumor angiogenesis and has become an important target for cancer therapy. Vatalanib succinate (PTK787 /ZK 222584) is a specific inhibitor of all three VEGF receptor (VEGF-R1, VEGF-R2 and VEGF-R3) tyrosine kinases, which shows antitumor and anti-angiogenic activity in cancer cells. (The product is for research use only.)
References
- PTK787 /ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
- Effects of PTK787 /ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model
- PTK787 /ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging
- Vascular endothelial growth factor receptor tyrosine kinase inhibitors: PTK787 /ZK 222584 (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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