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CAS RN: 1809-20-7 | Product Number: P0629

Diisopropyl Phosphite


Purity: >98.0%(GC)
Synonyms:
  • Diisopropyl Phosphonate
  • Phosphonic Acid Diisopropyl Ester
  • Phosphorous Acid Diisopropyl Ester
Product Documents:
25G
₹4,900.00
2   30  
500G
₹13,100.00
1   15  

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Product Number P0629
Purity / Analysis Method >98.0%(GC)
Molecular Formula / Molecular Weight C__6H__1__5O__3P = 166.16 
Physical State (20 deg.C) Liquid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Hygroscopic
CAS RN 1809-20-7
Reaxys Registry Number 1703675
PubChem Substance ID 87574790
SDBS (AIST Spectral DB) 4586
MDL Number

MFCD00117905

Specifications
Appearance Colorless to Almost colorless clear liquid
Purity(GC) min. 98.0 %
Properties (reference)
Boiling Point 79 °C/14 mmHg
Flash point 112 °C
Specific Gravity (20/20) 1.00
Refractive Index 1.41
Solubility in water Soluble
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 + H332 : Harmful if swallowed or if inhaled.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P271 : Use only outdoors or in a well-ventilated area.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
Related Laws:
RTECS# SZ7660000
Transport Information:
Application
H-Phosphonate-Mediated Amination of Quinoline N-Oxides with Trialkylamines

P0629

Typical procedure (R=H, R1=R2=R3=Et): Quinoline-N-oxide (145 mg, 1.0 mmol), triethylamine (304 mg, 3.0 mmol), diisopropyl phosphite (332 mg, 2.0 mmol) and CCl4 (0.5 mL) in THF (15 mL) is stirred at room temperature for 8 h. The solvent is evaporated under vacuum, and the residue is quenched with water (5 mL), extracted with ethyl acetate (3 × 5 mL). The combined organic layers are washed with brine (15 mL) and dried over Na2SO4. After filtration, the solvent is evaporated in vacuo. The crude product is purified by silica gel column chromatography (petroleum ether: ethyl acetate = 10:1) to give N, N-diethylquinolin-2-amine (143 mg, 83%) as a yellow oil.

References


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