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Maximum quantity allowed is 999
CAS RN: 548472-68-0 | Product Number: N1195
Nutlin-3

Purity: >95.0%(HPLC)
- rel-4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl]piperazin-2-one
Size | Unit Price | Hyderabad | Japan* | Quantity |
---|---|---|---|---|
10MG |
₹3,700.00
|
Contact Us | 14 |
|
50MG |
₹11,600.00
|
Contact Us | 26 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Product Number | N1195 |
Purity / Analysis Method | >95.0%(HPLC) |
Molecular Formula / Molecular Weight | C__3__0H__3__0Cl__2N__4O__4 = 581.49 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (-20°C) |
Condition to Avoid | Heat Sensitive |
CAS RN | 548472-68-0 |
PubChem Substance ID | 468592509 |
MDL Number | MFCD07784509 |
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 95.0 area% |
Specific rotation | -1.0 to +1.0 deg(C=0.2, CHCl3) |
NMR | confirm to structure |
Reference
- Nutlin-3 enhances the bortezomib sensitivity of p53-defective cancer cells by inducing paraptosis
- In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
- Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy
- Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy (a review)
- Recent advances in the therapeutic perspectives of nutlin-3 (a review)
References
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