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CAS RN: 641571-11-1 | Product Number: M2634
3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
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Purity: >98.0%(GC)(T)
Synonyms:
- 1-[3-Amino-5-(trifluoromethyl)phenyl]-4-methylimidazole
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
₹4,600.00
|
3 | 2 |
|
| 5G |
₹9,800.00
|
1 | 18 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | M2634 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__1H__1__0F__3N__3 = 241.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 641571-11-1 |
| Reaxys Registry Number | 11280392 |
| PubChem Substance ID | 253660623 |
| MDL Number | MFCD11846236 |
Specifications
| Appearance | White to Light gray to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 129.0 to 133.0 °C |
Properties (reference)
| Melting Point | 130 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
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Application
A Synthetic Intermediate of Nilotinib
This product has been used as a synthetic intermediate of nilotinib [N1296], a BCR-ABL tyrosine kinase inhibitor.
References
- Completely N1-Selective Palladium-Catalyzed Arylation of Unsymmetric Imidazoles: Application to the Synthesis of Nilotinib
- An efficient synthesis of nilotinib (AMN107)
- Designing Novel BCR-ABL Inhibitors for Chronic Myeloid Leukemia with Improved Cardiac Safety
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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