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CAS RN: 56974-61-9 | Product Number: G0464
Gabexate Mesylate
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Purity: >97.0%(N)
Synonyms:
- 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic Acid Ethyl Ester Mesylate
- Gabexate Methanesulfonate
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
₹11,300.00
|
4 | 15 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | G0464 |
| Purity / Analysis Method | >97.0%(N) |
| Molecular Formula / Molecular Weight | C__1__6H__2__3N__3O__4·CH__4O__3S = 417.48 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 56974-61-9 |
| Related CAS RN | 39492-01-8 |
| Reaxys Registry Number | 5702026 |
| PubChem Substance ID | 253660880 |
| Merck Index (14) | 4320 |
| MDL Number | MFCD00210299 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 94.0 area% |
| Purity(with Total Nitrogen) | min. 97.0 % |
| Melting point | 89.0 to 93.0 °C |
Properties (reference)
| Melting Point | 91 °C |
| Solubility (soluble in) | Methanol |
| Solubility (slightly sol. in) | Acetone |
| Solubility (insoluble in) | Ether |
GHS
Related Laws:
| RTECS# | DG2800800 |
Transport Information:
Application
Gabexate Mesylate: A Synthetic Non-Peptide Protease Inhibitor
Gabexate mesylate is a synthetic non-peptide protease inhibitor. It inhibits trypsin, kallikrein, thrombin, plasmin, C1 esterase, and etc. Gabexate mesylate inhibit thrombin and activated factor X, being independent of plasma antithrombin level. Gabexate mesylate is used as anticoagulants for the treatment of disseminated intravascular coagulation (DIC). (The product is for research purpose only.)
References
- FOY: [ethyl-p-(6-guanidinohexanoyloxy) benzoate] methanesulfonate as a serine proteinase inhibitor. I. Inhibition of thrombin and factor Xa in vitro
- Gabexate mesylate and pivmecillinam hydrochloride (a review)
- D. F. Weetman, Drugs Today 1978, 14, 411.
- Competitive inhibition of swine kidney copper amine oxidase by drugs: amiloride, clonidine, and gabexate mesylate
- Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-α producation by inhibiting activation of both nuclear factor-κB and activator protein-1 in human monocytes
- Gabexate mesilate inhibits colon cancer growth, invasion, and metastasis by reducing matrix metalloproteinases and angiogenesis
PubMed Literature
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