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CAS RN: 4143-62-8 | Product Number: D4794

3',4'-Dimethoxyflavone


Purity: >98.0%(GC)
Synonyms:
Product Documents:
200MG
₹2,900.00
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1G
₹10,800.00
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Product Number D4794
Purity / Analysis Method >98.0%(GC)
Molecular Formula / Molecular Weight C__1__7H__1__4O__4 = 282.30 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN 4143-62-8
Reaxys Registry Number 236749
PubChem Substance ID 354333484
MDL Number

MFCD00143009

Specifications
Appearance White to Light yellow powder to crystal
Purity(GC) min. 98.0 %
Melting point 151.0 to 155.0 °C
NMR confirm to structure
Properties (reference)
Melting Point 153 °C
Maximum Absorption Wavelength 334 nm (MeOH)
GHS
Related Laws:
RTECS# DJ3012950
Transport Information:
Application
3',4'-Dimethoxyflavone: An Inhibitor of Poly (ADP-Ribose) Polymerase (PARP) Enzymes

Genomic instability is a hallmark of cancer and is often the result of altered DNA repair capabilities in tumor cells. Poly (ADP-ribose) polymerases (PARPs) are enzymes responsible for DNA damage detection and repair factor recruitment. PARP inhibitors are able to interact with the binding site for the PARP cofactor NAD+ and trap PARP on DNA, and induce cell death through replication stress-induced mitotic catastrophe. It has been reported that 3',4'-dimethoxyflavone is a PARP inhibitor and has neuroprotective effects. (The product is for research use only.)

Reference

Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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