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CAS RN: 146535-11-7 | Product Number: D4601
AG-1296
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Purity: >98.0%(GC)
Synonyms:
- 6,7-Dimethoxy-2-phenylquinoxaline
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 5MG |
₹3,200.00
|
Contact Us | 27 |
|
| 25MG |
₹8,640.00
|
Contact Us | 30 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | D4601 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__4N__2O__2 = 266.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 146535-11-7 |
| Reaxys Registry Number | 7535310 |
| PubChem Substance ID | 468591271 |
| MDL Number | MFCD00270913 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 138.0 to 142.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 140 °C |
GHS
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Application
AG-1296: A Platelet-Derived Growth Factor Receptor (PDGFR) Kinase Inhibitor
AG-1296 is reported to inhibit selectively the platelet-derived growth factor (PDGF) receptor kinase and the PDGF-dependent DNA synthesis.
References
- Selective platelet-derived growth factor receptor kinase blockers reverse sis-transformation
- Phosphorylation Site-Specific Inhibition of Platelet-Derived Growth Factor β-Receptor Autophosphorylation by the Receptor Blocking Tyrphostin AG1296
- PDGF-receptor tyrosine kinase blocker AG1295 selectively attenuates smooth muscle cell growth in vitro and reduces neointimal formation after balloon angioplasty in swine
- Tethering of the platelet-derived growth factor β receptor to G-protein-coupled receptors. A novel platform for integrative signaling by these receptor classes in mammalian cells
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