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CAS RN: 106266-04-0 | Product Number: D3979
4-(2,4-Difluorobenzoyl)piperidine Hydrochloride
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Purity: >98.0%(HPLC)(N)
Synonyms:
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
₹11,900.00
|
3 | 31 |
|
| 25G |
₹14,600.00
|
2 | 20 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | D3979 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__2H__1__3F__2NO·HCl = 261.70 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 106266-04-0 |
| Reaxys Registry Number | 13515586 |
| PubChem Substance ID | 125307550 |
| SDBS (AIST Spectral DB) | 52822 |
| MDL Number | MFCD01313310 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
Properties (reference)
| Solubility in water | Soluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
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Application
A Synthetic Intermediate of Benzisoxazole Dopamine D2 and Serotonin Receptors Antagonists
This product has been used as a synthetic intermediate of benzisoxazole dopamine D2 and serotonin receptors antagonists, such as Iloperidone [I0926] and risperidone [R0087].
References
- Flow Synthesis in Hot Water: Synthesis of the Atypical Antipsychotic Iloperidone
- Improved process for the preparation of 3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl}-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone)
- l. Pongó, J. Reiter, G. Simig, G. Berecz, G. Clementis, P. Slégel, J. Szulágyi, L. Koncz, G. V. Donáth, K. Nagy, G. Körtvélyessy, WO2003042212 A1.
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