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CAS RN: 10416-59-8 | Product Number: B0510

N,O-Bis(trimethylsilyl)acetamide (25% in Acetonitrile) [Trimethylsilylating Reagent, for NH2 compounds]


Purity:
Synonyms:
  • TMS-BA (25% in Acetonitrile)
  • BSA (25% in Acetonitrile)
Product Documents:
12ML
₹1,800.00
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Product Number B0510
Physical State (20 deg.C) Liquid
Storage Temperature Refrigerated (0-10°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Moisture Sensitive,Heat Sensitive
Packaging and Container 12ML-Vial (View image)
CAS RN 10416-59-8
Reaxys Registry Number 1306669
PubChem Substance ID 87563534
MDL Number

MFCD00008270

Specifications
Appearance Colorless to Light yellow clear liquid
Effect test of TMS derivatization Effective as derivatization agent DL-Threonine
Properties (reference)
GHS
Pictogram Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H311 : Toxic in contact with skin.
H302 + H332 : Harmful if swallowed or if inhaled.
H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H370 : Causes damage to organs.
H373 : May cause damage to organs through prolonged or repeated exposure.
H225 : Highly flammable liquid and vapor.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P240 : Ground/bond container and receiving equipment.
P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking.
P233 : Keep container tightly closed.
P243 : Take precautionary measures against static discharge.
P241 : Use explosion-proof electrical/ ventilating/ lighting/ equipment.
P242 : Use only non-sparking tools.
P271 : Use only outdoors or in a well-ventilated area.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor.
P361 + P364 : Take off immediately all contaminated clothing and wash it before reuse.
P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P403 + P235 : Store in a well-ventilated place. Keep cool.
P405 : Store locked up.
Related Laws:
Transport Information:
UN Number UN1992
Class 3 / 6.1
Packing Group II
Application
Trimethylsilylating Reagent for GC Derivatization

Experimental procedure: ca. 1 mg of sample and 1 mL of TMS-BA is placed into a dry vessel (about 2 mL of vial is preferable). After sealing the vessel, the reaction is proceeded by shaking or heating (e.g. for leucine, threonine, by heating for 15 min at 125 °C) to result a transparent solution. And then it is directly injected into GC.

References


PubMed Literature


TCIMAIL
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