Maximum quantity allowed is 999
Please select the quantity
CAS RN: 796-42-9 | Product Number: A3339
AS-8351
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- N'-[(2-Hydroxynaphthalen-1-yl)methylene]isonicotinohydrazide
- N'-[(2-Hydroxy-1-naphthyl)methylene]isonicotinohydrazide
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 10MG |
₹3,300.00
|
Contact Us | 26 |
|
| 50MG |
₹9,900.00
|
Contact Us | 29 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | A3339 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__3N__3O__2 = 291.31 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| CAS RN | 796-42-9 |
| Reaxys Registry Number | 267907 |
| PubChem Substance ID | 468590241 |
| MDL Number | MFCD00033110 |
Specifications
| Appearance | White to Orange to Green powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 266 °C |
| Maximum Absorption Wavelength | 367(MeOH) nm |
GHS
Related Laws:
Transport Information:
Application
AS-8351: An Iron Chelator Inhibiting the Activity of Histone Demethylase
AS-8351 is reported to be an iron chelator with anti-tumor activity,1,2) and a histone demethylase inhibitor targeting KDM5B (JARID1B).3) (The product is for research purpose only.)
References
- 1) The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents II: the mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone
- 2) The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents III: the effect of the ligands on molecular targets involved in proliferation
- 3) Conversion of human fibroblasts into functional cardiomyocytes by small molecules
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.