Maintenance Notice (08:30 PM Mar 8, Sat - 00:30 AM Mar 9, Sun) : The website is scheduled for maintenance. The website will be available, but there may be some failures. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.197 | New tool "TCI SpectraViewer" | [Product Highlights] Amidine-based Ligands for... | Product Document Searching Made Easy by 2D Code!
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 120511-73-1 | Product Number: A2370
Anastrozole
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 100MG |
₹15,300.00
|
1 | ≥60 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | A2370 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__9N__5 = 293.37 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 120511-73-1 |
| Reaxys Registry Number | 8005958 |
| PubChem Substance ID | 135727309 |
| MDL Number | MFCD00866298 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 82.0 to 86.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 84 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | CZ1465000 |
Transport Information:
| UN Number | UN3439 |
| Class | 6.1 |
| Packing Group | III |
Application
Anastrozole: A Potent and Selective Aromatase Inhibitor
Anastrozole is a third generation, and a potent and selective aromatase inhibitor. Aromatase is responsible enzyme for the aromatization of androgens into estrogens in the periphery. Anastrozole inhibits aromatase and estrogen synthesis, resulting in suppressing tumor growth. Anastrozole alone or a combination agent with tamoxifen citrate [T2510] is used for the treatment for postmenopausal women with breast cancer. (The product is for research purpose only.)
References
- Influence of anastrozole (Arimidex), a selective, non-steroidal aromatase inhibitor, on in vivo aromatization and plasma estrogen levels in postmenopausal women with breast cancer
- The preclinical pharmacology of "Arimidex" (anastrozole; ZD1033) - a potent, selective aromatase inhibitor
- Inhibition of human drug metabolizing cytochromes P450 by anastrozole, a potent and selective inhibitor of aromatase
- Aromatase inhibitors in the treatment of breast cancer (a review)
- Development and validation of a simple and sensitive high performance liquid chromatographic method for the simultaneous determination of anastrozole, bicalutamide, tamoxifen, and their synthetic impurities
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.