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CAS RN: 471-05-6 | Product Number: Z0060
Zerumbone
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Purity: >98.0%(GC)
Synonyms:
- (2E,6E,10E)-2,6,9,9-Tetramethylcycloundeca-2,6,10-trien-1-one
- (2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 250MG |
€345.00
|
Contact Us | 25 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | Z0060 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__5H__2__2O = 218.34 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 471-05-6 |
| Reaxys Registry Number | 3199411 |
| MDL Number | MFCD03700769 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 63.0 to 67.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 65 °C |
GHS
Related Laws:
| RTECS# | GZ4817200 |
Transport Information:
| HS Number | 2914290090 |
Application
Zerumbone: A Monocyclic Sesquiterpene with Multiple Biological Activities
Zerumbone is a monocyclic sesquiterpene first isolated from rhizomes of wild ginger (Zingiber zerumbet Smith), which has been used locally in horticulture and folk medicine. Zerumbone has been found to possess multiple biological properties such as antiproliferative, antioxidant, anti-inflammatory, and anticancer activities.1-3) In addition, zerumbone inhibits the Hedgehog/GLI (Hh/GLI) signaling pathway and induces apoptosis in cancer cell lines.4,5) (The product is for research purpose only.)
References
- 1) Biomedical properties of a natural dietary plant metabolite, zerumbone, in cancer therapy and chemoprevention trials (a review)
- 2) Potential of zerumbone as an anti-cancer agent (a review)
- 3) Potential application of zerumbone in the prevention and therapy of chronic human diseases (a review)
- 4) Naturally occurring small-molecule inhibitors of hedgehog /GLI-mediated transcription
- 5) Role of Glioma-associated GLI1 Oncogene in Carcinogenesis and Cancertargeted Therapy (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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