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CAS RN: 4670-05-7 | Product Number: T3962
Theaflavin
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Purity: >98.0%(GC)
Synonyms:
- 3,4,6-Trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxychroman-2-yl]-5H-benzo[7]annulen-5-one
Product Documents:
| Size | Unit Price | Belgium | Japan* |
Shipping Information
|
|---|---|---|---|---|
| 5MG |
€129.00
|
2 | ≥40 | |
| 25MG |
€412.00
|
Contact Us | 26 |
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | T3962 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__9H__2__4O__1__2 = 564.50 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Moisture Sensitive,Heat Sensitive |
| CAS RN | 4670-05-7 |
| Reaxys Registry Number | 74271 |
| PubChem Substance ID | 468593041 |
| Merck Index (14) | 9274 |
| MDL Number | MFCD03427500 |
Specifications
| Appearance | Red to Dark red to Brown powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 240 °C |
| Specific Rotation | -274.8° (C=0.2,Acetone) |
| Maximum Absorption Wavelength | 462 nm (MeOH) |
GHS
Related Laws:
| RTECS# | DE8382900 |
Transport Information:
| HS Number | 2932990090 |
Application
Theaflavin: A Flavonoid with Diverse Biological Activities
Theaflavin is a flavonoid found in black tea that obtained by enzymatic oxidation during the fermentation process of tea leaves. It has been reported that theaflavin has diverse biological activities, including antioxidant, anticancer, and antiviral activities.1-3) In 2020, some studies have reported that theaflavin may be effective in suppressing the growth of SARS-CoV-2.4,5) In these reports, theaflavin has the potential to bind to RNA-dependent RNA polymerase, and to inhibit SARS-CoV-2 viral growth and activity. (The product is for research purpose only.)
References
- 1) Theaflavins in black tea and catechins in green tea are equally effective antioxidants
- 2) Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols
- 3) Synthesis of theaflavins and their functions (a review)
- 4) The potential chemical structure of anti-SARS-CoV-2 RNA-dependent RNA polymerase
- 5) High throughput virtual screening to discover inhibitors of the main protease of the coronavirus SARS-CoV-2
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