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Published TCIMAIL newest issue No.197
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CAS RN: 36062-04-1 | Product Number: T3587
Tetrahydrocurcumin
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Purity: >95.0%(GC)(T)
Synonyms:
- 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione
- 1,7-Bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 5G |
€85.00
|
1 | 5 |
| 25G |
€175.00
|
1 | 19 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | T3587 |
| Purity / Analysis Method | >95.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__2__1H__2__4O__6 = 372.42 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| CAS RN | 36062-04-1 |
| Reaxys Registry Number | 3485469 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 95.0 % |
| Purity(Neutralization titration) | min. 95.0 % |
| Melting point | 98.0 to 102.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 100 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2914500080 |
Application
Tetrahydrocurcumin: An Antioxidative Major Metabolite of Curcumin
Tetrahydrocurcumin (THC) is a major metabolite of curcumin [C0434, C2302] that lacks the α, β-unsaturated carbonyl moiety and occurs naturally in turmeric.1) The interest in THC research has recently increased due to its superiority over curcumin in water solubility, chemical stability, bioavailability, and antioxidant activity. Many studies have indicated that THC exhibits higher antioxidant activity, but curcumin appears to bind to and modulate the activities of a wide variety of targets.2-4) Therefore, THC is expected to act as a chemo-preventative agent. (The product is for research purpose only.)
References
- 1) Biotransformation of curcumin through reduction and glucuronidation in mice
- 2) Curcumin differs from tetrahydrocurcumin for molecular targets, signaling pathways and cellular responses (a review)
- 3) Chemopreventative effects of tetrahydrocurcumin on human diseases (a review)
- 4) The cancer chemopreventive and therapeutic potential of tetrahydrocurcumin (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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