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Published TCIMAIL newest issue No.197
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CAS RN: 21256-18-8 | Product Number: O0377
Oxaprozin
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 4,5-Diphenyl-2-oxazolepropionic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 5G |
€44.00
|
1 | 16 |
| 25G |
€140.00
|
Contact Us | 19 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | O0377 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__1__5NO__3 = 293.32 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 21256-18-8 |
| Reaxys Registry Number | 1083168 |
| PubChem Substance ID | 160871033 |
| SDBS (AIST Spectral DB) | 53268 |
| Merck Index (14) | 6924 |
| MDL Number | MFCD00215977 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 161.0 to 165.0 °C |
Properties (reference)
| Melting Point | 163 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Methanol |
GHS
| Hazard Statements | H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. |
Related Laws:
| EC Number | 244-296-1 |
| RTECS# | RP6990000 |
Transport Information:
| HS Number | 2934999090 |
Application
Studies on Inhibition of Cyclooxygenase (COX)
References
- Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs
- In vitro scavenging activity for reactive oxygen and nitrogen species by nonsteroidal anti-inflammatory indole, pyrrole, and oxazole derivative drugs
- Oxaprozin. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy
- P. A. Todd, R. N. Brogden, Drugs 1986, 32, 291.
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