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CAS RN: 76963-41-2 | Product Number: N0933
Nizatidine
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Purity: >97.0%(T)(HPLC)
Synonyms:
- N-[2-[[[2-[(Dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 5G |
€49.00
|
Contact Us | Contact Us |
| 25G |
€170.00
|
Contact Us | Contact Us |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | N0933 |
| Purity / Analysis Method | >97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__2H__2__1N__5O__2S__2 = 331.45 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 76963-41-2 |
| Reaxys Registry Number | 4846056 |
| PubChem Substance ID | 253661718 |
| Merck Index (14) | 6660 |
| MDL Number | MFCD00865660 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 130.0 to 134.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 132 °C |
| Solubility in water | Slightly soluble |
| Solubility (soluble in) | dichloromethane, Methanol |
| Solubility (insoluble in) | Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | KM6565000 |
Transport Information:
| HS Number | 2934100090 |
Application
ヒスタミンH2受容体アンタゴニスト，ニザチジン
Nizatidine is a histamine H2-receptor antagonist that inhibits gastric acid secretion. (The product is for research purpose only.)
References
- Nizatidine. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in peptic ulcer disease (a review)
- Nizatidine (a review on description, synthesis, physical properties, stability and degradation, drug metabolites and pharmacokinetics)
- Inhibition of drug metabolism in human liver microsomes by nizatidine, cimetidine and omeprazole
- Simple and universal HPLC-UV method to determine cimetidine, ranitidine, famotidine and nizatidine in urine: Application to the analysis of ranitidine and its metabolites in human volunteers
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