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CAS RN: 27848-84-6 | Product Number: N0904
Nicergoline
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Purity: >98.0%(T)(HPLC)
Synonyms:
- [(8R,10S)-10-Methoxy-1,6-dimethylergolin-8-yl]methyl 5-Bromopyridine-3-carboxylate
- 5-Bromopyridine-3-carboxylic Acid [(8R,10S)-10-Methoxy-1,6-dimethylergolin-8-yl]methyl Ester
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 100MG |
€26.00
|
2 | ≥100 |
| 1G |
€178.00
|
1 | 25 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | N0904 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__4H__2__6BrN__3O__3 = 484.39 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 27848-84-6 |
| Reaxys Registry Number | 903548 |
| PubChem Substance ID | 135727224 |
| Merck Index (14) | 9496 |
| MDL Number | MFCD00869626 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 134.0 to 138.0 °C |
| Specific rotation [a]20/D | +5.2 to +6.2 deg(C=5, EtOH(95vol%)) |
Properties (reference)
| Melting Point | 136 °C |
| Specific Rotation | 6.0° (C=5,EtOH(95vol%)) |
| Solubility (soluble in) | Ethanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 248-694-6 |
| RTECS# | KE6341000 |
Transport Information:
| HS Number | 2933998090 |
Application
Pharmacological Studies
References
- Nicergoline inhibits T-type calcium channels in rat isolated hippocampal CA1 pyramidal neurons
- K. Takahashi, N. Akaike, Br. J. Pharmacol. 1990, 100, 705.
- Modulation of hippocampal ACh release by chronic nicergoline treatment in freely moving young and aged
- Cholinergic deficits in aged rat brain are corrected with nicergoline
- Pharmacological study of nicergoline. Effects on regional cerebral blood flows and arterial carbon dioxide and oxygen pressure and pH in rats under cyanide-induced histotoxic anoxia
- K. Shintomi, Arzneim.-Forsch. 1991, 41, 885.
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