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CAS RN: 71125-38-7 | Product Number: M1959
Meloxicam
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Purity: >98.0%(HPLC)
Synonyms:
- 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 5G |
€18.00
|
6 | ≥80 |
| 25G |
€55.00
|
2 | ≥40 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | M1959 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__3N__3O__4S__2 = 351.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 71125-38-7 |
| Reaxys Registry Number | 5886369 |
| PubChem Substance ID | 87560523 |
| Merck Index (14) | 5826 |
| MDL Number | MFCD00868752 |
Specifications
| Appearance | White to Light yellow to Green powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 96.0 % |
Properties (reference)
| Melting Point | 255 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | DL0702000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2935909099 |
Application
Meloxicam: A Preferential Cyclooxygenase-2 (COX-2) Inhibitor
Meloxicam is a non-steroidal anti-inflammatory drug (NSAID), and a preferential cyclooxygenase-2 (COX-2) inhibitor. The mechanism of action is mainly by inhibition of the enzyme COX in the arachidonic acid metabolism pathway, resulting in reduced prostaglandin synthesis. In theory, a drug that selectively inhibited COX-2 might block inflammation, pain, and fever produced by prostaglandins while reducing the side effects (gastric erosions and ulcers) associated with inhibition of COX-1. (The product is for research purpose only.)
References
- Meloxican: Influence on arachidonic acid metabolism: Part 1. In vitro findings
- Meloxican: Influence on arachidonic acid metabolism: Part II. In vivo findings
- Evaluation of pharmacological profile of meloxicam as an anti-inflammatory agent, with particular reference to its relative selectivity for cyclooxygenase-2 over cyclooxygenase-1
- Differential inhibition of cyclooxygenases-1 and -2 by meloxicam and its 4’-isomer
- Meloxicam: a reappraisal of pharmacokinetics, efficacy and safety (a review)
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