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Published TCIMAIL newest issue No.197
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CAS RN: 82-02-0 | Product Number: K0039
Khellin
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Purity: >95.0%(GC)
Synonyms:
- 4,9-Dimethoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one
- Visammin
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 1G |
20,00 €
|
Contact Us | 4 |
| 5G |
65,00 €
|
1 | 13 |
| 25G |
222,00 €
|
2 | 3 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | K0039 |
| Purity / Analysis Method | >95.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__2O__5 = 260.25 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 82-02-0 |
| Reaxys Registry Number | 263185 |
| PubChem Substance ID | 87571971 |
| SDBS (AIST Spectral DB) | 16671 |
| Merck Index (14) | 5309 |
| MDL Number | MFCD00005007 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 95.0 % |
| Melting point | 150.0 to 154.0 °C |
| Solubility in hot Methanol | almost transparency |
Properties (reference)
| Melting Point | 152 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. |
Related Laws:
| EC Number | 201-392-8 |
| RTECS# | LV1050000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2932990090 |
Application
Khellin: A Mild Photosensitizer
Khellin, a naturally occurring furochromone, has a chemical structure similar to a photosensitizing agent psoralen [P2077] which has been reported to be an efficient agent for treating vitiligo and psoriasis when combined with UVA irradiation. Khellin has been reported to have phototherapeutic properties that are similar to those of the psoralens, but with substantially lower phototoxic effects and DNA mutation effects. As opposed to psoralens, khellin did not induce skin phototoxicity with UVA but it induced repigmentation similar to psoralens. (The product is for research purpose only.)
References
- Phototherapeutic, photobiologic, and photosensitizing properties of khellin
- Khellin, a naturally occurring furochromone, used for the photochemotherapy of skin diseases: mechanism of action
- Treatment of vitiligo with khellin liposomes, ultraviolet light and blister roof transplantation
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