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Published TCIMAIL newest issue No.197
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CAS RN: 59-92-7 | Product Number: D0600
3-(3,4-Dihydroxyphenyl)-L-alanine
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Purity: >98.0%(T)(HPLC)
Synonyms:
- L-DOPA
- Levodopa
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 5G |
19,00 €
|
9 | ≥60 |
| 25G |
60,00 €
|
7 | 38 |
| 100G |
161,00 €
|
2 | 30 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D0600 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__9H__1__1NO__4 = 197.19 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive |
| CAS RN | 59-92-7 |
| Reaxys Registry Number | 2215169 |
| PubChem Substance ID | 87567249 |
| SDBS (AIST Spectral DB) | 2216 |
| Merck Index (14) | 5464 |
| MDL Number | MFCD00002598 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | -11.0 to -13.0 deg(C=5, 1mol/L HCl) |
| Solubility in 1mol/L HCl | almost transparency |
Properties (reference)
| Melting Point | 278 °C |
| Specific Rotation | -12° (C=5,1mol/L HCl) |
| Solubility in water | Slightly soluble |
| Solubility (insoluble in) | Benzene, Chloroform, Ethanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 200-445-2 |
| RTECS# | AY5600000 |
Transport Information:
| HS Number | 2922500090 |
Application
L-DOPA (Levodopa): A Precursor in the Biosynthesis of Dopamine
L-DOPA (Levodopa) is a bio-derivative of amino acid L-tyrosine [T0550]. It is a precursor in the biosynthesis of dopamine [A0305], noradrenaline [A0906] and adrenaline [A0173], and is used to increase dopamine levels in brain.
References
- Pharmacokinetics of levodopa
- Neurobiology of L-DOPAergic systems
- L-DOPA: From a biologically inactive amino acid to a successful therapeutic agent. Historical review article
- Molecular mechanisms of L-DOPA-induced dyskinesia
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