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Published TCIMAIL newest issue No.197
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CAS RN: 6199-67-3 | Product Number: C3442
Cucurbitacin B
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Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 5MG |
€151.00
|
1 | 39 |
| 25MG |
€504.00
|
1 | ≥40 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | C3442 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__3__2H__4__6O__8 = 558.71 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 25MG-Glass Bottle with Plastic Insert (View image), 5MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 6199-67-3 |
| Reaxys Registry Number | 2068869 |
| PubChem Substance ID | 354335232 |
| Merck Index (14) | 2614 |
| MDL Number | MFCD07778083 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Water | max. 5.0 % |
Properties (reference)
| Melting Point | 179 °C |
| Maximum Absorption Wavelength | 290(EtOH) nm |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 : Fatal if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | RC6190000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | II |
| HS Number | 2915390090 |
Application
Cucurbitacin B: A Triterpenoid Reported as a Promising Antitumor Agent
Cucurbitacin B is a triterpenoid compound isolated from Cucurbitaceae and various plants used as folk medicine in Asian countries, and has recently emerged as a potent antitumor agent. Cucurbitacin B is reported to have anti-proliferation effects on a variety of tumors, and the mechanism of action is still controversial. (The product is for research purpose only.)
References
- Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme
- Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells
- Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration
- Triterpenoids for cancer prevention and treatment: current status and future prospects (a review)
- A review on the medicinally important plants of the family Cucurbitaceae (a review)
PubMed Literature
Articles/Brochures
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