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Published TCIMAIL newest issue No.197
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CAS RN: 635-65-4 | Product Number: B0460
Bilirubin
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Purity: >80.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 100MG |
43,00 €
|
Contact Us | 27 |
| 1G |
218,00 €
|
2 | ≥40 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | B0460 |
| Purity / Analysis Method | >80.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__3__3H__3__6N__4O__6 = 584.67 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive,Heat Sensitive |
| CAS RN | 635-65-4 |
| PubChem Substance ID | 87563495 |
| SDBS (AIST Spectral DB) | 5074 |
| Merck Index (14) | 1218 |
| MDL Number | MFCD00005499 |
Specifications
| Appearance | Orange to Brown powder to crystal |
| Purity(HPLC) | min. 80.0 area% |
| Lambda max. | 450.0 to 454.0 nm(CHCl3) |
| Molar extinction coefficient | 56,000 to 61,000(CHCl3, 450.0 to 454.0 nm) |
| NMR | confirm to structure |
Properties (reference)
| Maximum Absorption Wavelength | 452(CHCl3) nm |
GHS
Related Laws:
| EC Number | 211-239-7 |
| RTECS# | DU3038000 |
Transport Information:
| HS Number | 2933998090 |
Application
Bilirubin: The End Product of Heme Catabolism with Interesting Biochemical and Biological Properties
Bilirubin, the principal bile pigment, is the end product of heme catabolism, formed when heme is cleaved by heme oxygenase-1 (HO-1). HO-1 catabolizes heme into three products: biliverdin (which is rapidly converted to bilirubin by biliverdin reductase), carbon monoxide (CO) and free iron ion (Fe3+). For many years, bilirubin was thought as a waste product with no physiological function. But recently, HO-1 has been recognized to have immunomodulatory, antioxidant and anti-inflammatory properties.1,2) And then, bilirubin has also been recognized to have a number of new and interesting biochemical and biological properties.3,4) (The product is for research purpose only.)
References
- 1) Heme oxygenase-1: unleashing the protective properties of heme (a review)
- 2) Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications (a review)
- 3) Bilirubin: An endogenous product of heme degradation with both cytotoxic and cytoprotective properties (a review)
- 4) Bilirubin chemistry and metabolism; harmful and protective aspects (a review)
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