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CAS RN: 14028-44-5 | Product Number: A2499
Amoxapine
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Purity: >97.0%(GC)(T)
Synonyms:
- 2-Chloro-11-(1-piperazinyl)dibenzo[b,f][1,4]oxazepine
Product Documents:
| Size | Unit Price | Belgium | Japan* |
|---|---|---|---|
| 1G |
€115.00
|
4 | ≥100 |
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A2499 |
| Purity / Analysis Method | >97.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__7H__1__6ClN__3O = 313.79 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 14028-44-5 |
| PubChem Substance ID | 181085854 |
| Merck Index (14) | 576 |
| MDL Number | MFCD00069210 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 97.0 % |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 178.0 to 182.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 179 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H302 : Harmful if swallowed. H370 : Causes damage to organs. H341 : Suspected of causing genetic defects. H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P273 : Avoid release to the environment. P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. |
Related Laws:
| EC Number | 237-867-1 |
| RTECS# | HQ4025500 |
Transport Information:
| HS Number | 2934999090 |
Application
Studies on the Neuropharmacology of Amoxapine
References
- Pharmacological profile of antidepressants and related compounds at human monoamine transporters
- Opioid receptors and neuropeptides in the CNS in rats treated chronically with amoxapine or amitriptyline
- Differential effects of the tricyclic antidepressant amoxapine on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters
- Is amoxapine an atypical antipsychotic? Positron-emission tomography investigation of its dopamine2 and serotonin2 occupancy
- Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine
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