text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 134678-17-4 | Product Number: L0217

Lamivudine


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 3TC
  • (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
Product Documents:
100MG
$39.00
27   6   It can be shipped in about 2 weeks after ordering
1G
$218.00
8   0   It can be shipped in about 2 weeks after ordering

* Please contact our distributors or TCI to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.


Supplemental Product Information:

This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.

Product Number L0217
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__8H__1__1N__3O__3S = 229.25 
Physical State (20 deg.C) Solid
Storage Temperature Frozen (<0°C)
Condition to Avoid Heat Sensitive
Packaging and Container 100MG-Glass Bottle with Plastic Insert (View image),  1G-Glass Bottle with Plastic Insert (View image)
CAS RN 134678-17-4
Reaxys Registry Number 5480511
PubChem Substance ID 87560180
Merck Index (14) 5352
MDL Number

MFCD00869739

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 175.0 to 179.0 °C
Specific rotation [a]20/D -137.0 to -147.0 deg(C=1, methanol)
NMR confirm to structure
Properties (reference)
Melting Point 177 °C
Specific Rotation -142° (C=1,MeOH)
Solubility in water Soluble
Degree of solubility in water 70,000 mg/l   20 °C
Solubility (soluble in) Methanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H373 : May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P314 : Get medical advice/ attention if you feel unwell.
Related Laws:
RTECS# UW7361333
Transport Information:
H.S.code* 2934.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Lamivudine: An L-Nucleoside Reverse Transcriptase Inhibitor

Lamivudine is a nucleoside reverse transcriptase inhibitor that active against HIV1, HIV2, and hepatitis B. Lamivudine is a synthetic L-nucleoside analogue of the naturally occurring D-nucleoside 2’-deoxycytidine. Intracellularly, lamivudine is converted by cellular enzymes to the active metabolite, lamivudine-5'-triphosphate. The triphosphate inhibits the activity of viral reverse transcriptase both by competing with the natural substrate, 2’-deoxycytidine-5'-triphosphate, and by its incorporation into viral DNA causing termination of viral DNA chain. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.

The requested SDS is not available.

Please Contact Us for more information.

Specifications
C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.

The product with the lot number searched for has been discontinued and no related documentation is available.

Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.

A sample C of A for this product is not available at this time.

Analytical Charts
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.

The requested analytical chart is not available. Sorry for the inconvenience.

The product with the lot number searched for has been discontinued and no related documentation is available.

Other Documents

Session Status
Your session will timeout in 10 minutes. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page. minute. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page.

Your session has timed out. You will be redirected to the HOME page.