text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 70288-86-7 | Product Number: I0819

Ivermectin


Purity: >93.0%(HPLC)
Synonyms:
  • MK-933
Product Documents:
1G
$68.00
13   ≥40  Contact Us
5G
$208.00
9   ≥40  Contact Us

* Please contact our distributors or TCI to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.


Supplemental Product Information:

This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.

Product Number I0819
Purity / Analysis Method >93.0%(HPLC)
Molecular Formula / Molecular Weight C__4__8H__7__4O__1__4 = 875.11 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Condition to Avoid Heat Sensitive
Packaging and Container 1G-Glass Bottle with Plastic Insert (View image)
CAS RN 70288-86-7
Reaxys Registry Number 8400552
PubChem Substance ID 468592054
Merck Index (14) 5248
MDL Number

MFCD00869511

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 93.0 area%
NMR confirm to structure
Properties (reference)
Melting Point 155 °C
Solubility (soluble in) Diethyl ether, Methanol, Ethanol
GHS
Pictogram Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H300 : Fatal if swallowed.
H361 : Suspected of damaging fertility or the unborn child.
H362 : May cause harm to breast-fed children.
H410 : Very toxic to aquatic life with long lasting effects.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P263 : Avoid contact during pregnancy/ while nursing.
P273 : Avoid release to the environment.
P260 : Do not breathe dusts or mists.
P270 : Do not eat, drink or smoke when using this product.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P391 : Collect spillage.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# IH7891500
Transport Information:
UN Number UN2811
Class 6.1
Packing Group I
H.S.code* 2932.20-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Autophagy research / Mitophagy research

References


Application
Ivermectin: A Semisynthetic Anthelmintic Agent with Antiviral Activity

Ivermectin is a semisynthetic anthelmintic agent derived from the avermectins isolated from the fermentation products of Streptomyces avermitilis.1,2) Ivermectin contains B1a (C48H74O14) and B1b (C47H72O14), but the main component is B1a as shown in the figure. The mechanism of action of ivermectin is not fully understood, but it is strongly suggested to be related to glutamate-gated chloride channels in the muscles and nerves of nematode.2) Ivermectin binds with high affinity to glutamatergic chloride channels of nematode. As the result, the nematode is thought to be paralyzed. In addition, it has recently been reported that ivermectin has a broad spectrum of antiviral activity in vitro, including SARS-CoV-2.3,4) (The product is for research purpose only.)

References


Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.

The requested SDS is not available.

Please Contact Us for more information.

Specifications
C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.

The product with the lot number searched for has been discontinued and no related documentation is available.

Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.

A sample C of A for this product is not available at this time.

Analytical Charts
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.

The requested analytical chart is not available. Sorry for the inconvenience.

The product with the lot number searched for has been discontinued and no related documentation is available.

Other Documents

Session Status
Your session will timeout in 10 minutes. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page. minute. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page.

Your session has timed out. You will be redirected to the HOME page.