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Published TCIMAIL newest issue No.197
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CAS RN: 427-51-0 | Product Number: C2942
Cyproterone Acetate
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Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
€74.00
|
1 | 2 |
|
| 1G |
€234.00
|
Contact Us | 7 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | C2942 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__4H__2__9ClO__4 = 416.94 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 427-51-0 |
| Reaxys Registry Number | 2342172 |
| PubChem Substance ID | 253660432 |
| Merck Index (14) | 2774 |
| MDL Number | MFCD00864671 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 206.0 to 211.0 °C |
| Specific rotation [a]20/D | +148.0 to +156.0 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 209 °C |
| Specific Rotation | 152° (C=1,CHCl3) |
| Maximum Absorption Wavelength | 281(MeOH) nm |
| Solubility in water | Insoluble |
| Degree of solubility in water | 52 mg/l 25 °C |
| Solubility (soluble in) | Methanol |
| Solubility (slightly sol. in) | Ethanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H360 : May damage fertility or the unborn child. H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| EC Number | 207-048-3 |
| RTECS# | GZ2230000 |
Transport Information:
| HS Number | 2937290000 |
Application
Cyproterone Acetate: A Synthetic Progestogen with Antiandrogenic Activity
Cyproterone acetate is a synthetic progestogen, which have antiandrogenic activity. It acts mainly by blocking androgen receptors, but also reduces the activity of skin 5α-reductase in sebaceous glands and hair follicles. It is primarily used in the treatment of androgen-related conditions such as acne, androgen dependent alopecia and prostate cancer. (The product is for research purpose only.)
References
- The antiandrogen cyproterone acetate: discovery, chemistry, basic pharmacology, clinical use and tool in basic research (a review)
- Antiandrogens: selective androgen receptor modulators (a review)
- Progestogens with antiandrogenic properties (a review)
- Antiandrogens in the treatment of prostate cancer (a review)
PubMed Literature
Articles/Brochures
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