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CAS RN: 148741-30-4 | Product Number: T3696
Tyrphostin AG 879
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Purity: >98.0%(HPLC)
Synonyms:
- (E)-2-Cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enethioamide
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5MG |
£116.00
|
Contact Us | 13 |
|
| 25MG |
£433.00
|
Contact Us | 13 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | T3696 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__4N__2OS = 316.46 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 148741-30-4 |
| Reaxys Registry Number | 9071348 |
| PubChem Substance ID | 468592899 |
| MDL Number | MFCD00236450 |
Specifications
| Appearance | Light yellow to Yellow to Orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 230.0 to 234.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 232 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P261 : Avoid breathing dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. |
Related Laws:
| RTECS# | UD1980000 |
Transport Information:
| HS Number | 2930909599 |
Application
Ttyrphostin AG 879: A RTK Inhibitor
RTKs (Receptor tyrosine kinases), transmembrane glycoproteins present on cell surface, are important molecules in biological phenomenon to control basic cell activities such as proliferation, differentiation, survival and death. It has been reported that tyrphostin AG 879 inhibits RTKs with anti-proliferative activities against cancer cells and viruses. (The product is for research purpose only.)
References
- The tyrosine kinase inhibitor tyrphostin blocks the cellular actions of nerve growth factor
- Synergy of Epidermal Growth Factor Receptor Kinase Inhibitor AG1478 and ErbB2 Kinase Inhibitor AG879 in Human Colon Carcinoma Cells Is Associated with Induction of Apoptosis
- Receptor tyrosine kinase inhibitors block multiple steps of influenza A virus replication
Product Documents (Note: Some products will not have analytical charts available.)
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