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Published TCIMAIL newest issue No.197
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CAS RN: 242478-38-2 | Product Number: S0944
Solifenacin Succinate
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Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
£30.00
|
2 | 34 |
|
| 100MG |
£83.00
|
3 | 4 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | S0944 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__2__6N__2O__2·C__4H__6O__4 = 480.56 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 242478-38-2 |
| Related CAS RN | 242478-37-1 |
| PubChem Substance ID | 253662487 |
| Merck Index (14) | 8712 |
| MDL Number | MFCD09952287 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 %(total of Ion-Pair) |
| Melting point | 145.0 to 149.0 °C |
Properties (reference)
| Melting Point | 147 °C |
| Solubility (slightly sol. in) | Ethanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | NW7136000 |
Transport Information:
| HS Number | 2933499090 |
Application
Solifenacin Succinate: Selective M3 Muscarinic Receptor Antagonist
Solifenacin succinate is a selective M3 muscarinic receptor antagonist. It is used for the treatment of overactive bladder (OAB). For your reference, [P2215] is a key synthetic intermediate of solifenacin succinate. (The product is for research purpose only.)
References
- M3 receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland
- In vitro and in vivo tissue selectivity profile of solifenacin succinate (YM905) for urinary bladder over salivary gland in rats
- Comparison of in vitro selectivity profiles of solifenacin succinate (YM905) and current antimuscarinic drugs in bladder and salivary glands: a Ca2+ mobilization study in monkey cells
- Synthesis and Antimuscarinic Properties of Quinuclidin-3-yl 1,2,3,4-Tetrahydroisoquinoline-2-carboxylate Derivatives as Novel Muscarinic Receptor Antagonists
- Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents
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