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CAS RN: 857036-77-2 | Product Number: R0277
Cediranib Maleate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Recentin
- AZD-2171 Maleate
- 4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline Maleate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 10MG |
£122.00
|
Contact Us | 22 |
|
| 50MG |
£426.00
|
Contact Us | ≥60 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | R0277 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__2__7FN__4O__3·C__4H__4O__4 = 566.59 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 857036-77-2 |
| Reaxys Registry Number | 14422486 |
| MDL Number | MFCD27665457 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
| HS Number | 2933998090 |
Application
Cediranib Maleate: A VEGF Receptor Tyrosine Kinase Inhibitor
Receptors for VEGF (vascular endothelial growth factor-A) play a central role in vasculogenesis and angiogenesis and are therefore targets for cancer therapy. Cediranib (AZD2171) [C3918] and its water-soluble maleate are VEGF receptor tyrosine kinase inhibitors used in cancer research. (The product is for research use only.)
References
- AZD2171 : A highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer
- The tyrosine kinase inhibitor cediranib for non-small cell lung cancer and other thoracic malignancies (a review)
- Cediranib , a pan-VEGFR inhibitor, and olaparib, a PARP inhibitor, in combination therapy for high grade serous ovarian cancer
- Solubility and stability of cediranib maleate
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
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Specifications
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