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Published TCIMAIL newest issue No.197
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CAS RN: 475-83-2 | Product Number: N1170
Nuciferine
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Purity: >97.0%(GC)
Synonyms:
- 1,2-Dimethoxy-6αβ-aporphine
- (R)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 250MG |
£542.00
|
Contact Us | 21 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | N1170 |
| Purity / Analysis Method | >97.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__1NO__2 = 295.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 475-83-2 |
| Reaxys Registry Number | 91202 |
| PubChem Substance ID | 468592496 |
| MDL Number | MFCD01664592 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 97.0 % |
| Specific rotation | -148 to -155 deg(C=0.5, EtOH) |
Properties (reference)
| Melting Point | 166 °C |
| Specific Rotation | -152° (C=0.5,EtOH) |
| Maximum Absorption Wavelength | 270(H2O) nm |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | CE0350000 |
Transport Information:
| UN Number | UN1544 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2939799090 |
Application
Nuciferine: An Aporphine Alkaloid with Several Pharmacological Activities
Nuciferine is an aporphine alkaloid contained in lotus leaves (N. nucifera Gaertn), which is a raw material in Chinese medicinal herb for weight loss. Nuciferine has been reported to possess several pharmacological activities, including insulin secretagogue,1) anti-cancer,2,3) anti-hyperlipidemia4) and anti-inflammatory4) activities. (The product is for research purpose only.)
References
- 1) Nuciferine stimulates insulin secretion from beta cells-an in vitro comparison with glibenclamide
- 2) Nuciferine, extracted from Nelumbo nucifera Gaertn, inhibits tumor-promoting effect of nicotine involving Wnt/β-catenin signaling in non-small cell lung cancer
- 3) Identification of the anti-tumor activity and mechanisms of nuciferine through a network pharmacology approach
- 4) Nuciferine restores potassium oxonate-induced hyperuricemia and kidney inflammation in mice
Product Documents (Note: Some products will not have analytical charts available.)
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