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Published TCIMAIL newest issue No.197
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CAS RN: 59937-28-9 | Product Number: M2674
Malotilate
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Purity: >98.0%(GC)
Synonyms:
- Diisopropyl (1,3-Dithiol-2-ylidene)malonate
- (1,3-Dithiol-2-ylidene)malonic Acid Diisopropyl Ester
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
£54.00
|
2 | 1 |
|
| 5G |
£269.00
|
1 | 2 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | M2674 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__2H__1__6O__4S__2 = 288.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 59937-28-9 |
| Reaxys Registry Number | 7481938 |
| PubChem Substance ID | 253662468 |
| Merck Index (14) | 5712 |
| MDL Number | MFCD00867646 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 59.0 to 63.0 °C |
Properties (reference)
| Melting Point | 61 °C |
| Solubility (soluble in) | Benzene, Methanol, Ether |
GHS
Related Laws:
| EC Number | 261-987-3 |
| RTECS# | OO0970000 |
Transport Information:
| HS Number | 2934999090 |
Application
マロチラートの抗線維化特性と肝臓保護作用
Malotilate is an agent with antifibrotic and hepatoprotective properties in several animal models. It is used for the treatment of liver disease. (The product is for research purpose only.)
References
- Hepatoprotection by malotilate against carbon tetrachloride-alcohol-induced liver fibrosis
- Preventive effect of malotilate on carbon tetrachloride-induced liver damage and collagen accumulation in the rat
- Malotilate, a hepatoprotectant, suppresses CYP2E1 expression in rats
- Inhibitory effects of malotilate on invasion and metastasis of rat mammary carcinoma cells by modifying the functions of vascular endothelial cells
- Fibroblast-migration in a wound model of ascorbic acid-supplemented three-dimensional culture system: the effects of cytokines and malotilate, a new wound healing stimulant, on cell-migration
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