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Published TCIMAIL newest issue No.197
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CAS RN: 22373-78-0 | Product Number: M2573
Monensin Sodium Salt
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Purity: >98.0%(T)
Synonyms:
- Monensin A Sodium Salt
- Sodium Monensin
- Sodium (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2S,2'R,3'S,5R,5'R)-2-Ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-[2,2'-bifuran]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methylpentanoate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
£49.00
|
2 | 38 |
|
| 5G |
£164.00
|
1 | 12 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | M2573 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__3__6H__6__1NaO__1__1 = 692.86 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 22373-78-0 |
| PubChem Substance ID | 468592207 |
| MDL Number | MFCD00077826 |
Specifications
| Appearance | White to Almost white powder to crystaline |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +55.0 to +60.0 deg(C=1.0, MeOH) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 264 °C(dec.) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 : Fatal if swallowed. H371 : May cause damage to organs. H373 : May cause damage to organs through prolonged or repeated exposure. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. |
Related Laws:
| EC Number | 244-941-7 |
| RTECS# | JH2830000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | II |
| HS Number | 2941900000 |
Application
Exosome research
References
- Stimulating the Release of Exosomes Increases the Intercellular Transfer of Prions
- Exosome Release Is Regulated by a Calcium-dependent Mechanism in K562 Cells
Application
Monensin Sodium Salt: A Monovalent Ion-Selective Ionophore Antibiotic
Monensin sodium salt is a monovalent ion-selective ionophore antibiotic, and facilitates the transmembrane exchange of principally sodium ions for protons, and therefore it shows a variety of biological properties including Golgi. Through its ability to affect pH and the sodium-potassium balance of a cell, monensin can induce cell death in Gram-positive bacteria. (The product is for research purpose only.)
References
- Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity (a review)
- Forty years of monensin for the control of coccidiosis in poultry (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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