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Published TCIMAIL newest issue No.197
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CAS RN: 2140-61-6 | Product Number: M1931
5-Methylcytidine
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
£97.00
|
2 | ≥40 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | M1931 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__5N__3O__5 = 257.25 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 2140-61-6 |
| Reaxys Registry Number | 89657 |
| PubChem Substance ID | 87560073 |
| MDL Number | MFCD00006548 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +13.0 to +17.0 deg(C=2, H2O) |
Properties (reference)
| Melting Point | 211 °C(dec.) |
| Specific Rotation | 15° (C=2,H2O) |
| Solubility in water | Soluble |
GHS
Related Laws:
| EC Number | 218-390-8 |
Transport Information:
| HS Number | 2940000080 |
Application
5-Methylcytidine: An Important Base-modified Ribonucleoside in Epigenetics
5-Methylcytidine (m5C) is a modified ribonucleoside that has long been known to be present in tRNA and rRNA.1) It is subject to oxidative processing in vivo to form 5-(hydroxymethyl)cytidine (hm5C) [H1863], which has roles in cell viability and development through these effects on RNA as follows; RNA structure and translation efficiency.2,3)
References
- 1) Transcriptome-wide mapping of 5-methylcytidine RNA modifications in bacteria, archaea, and yeast reveals m5C within archaeal mRNAs
- 2) Formation and Abundance of 5-Hydroxymethylcytosine in RNA
- 3) Epitranscriptome sequencing technologies: decoding RNA modifications (a review)
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