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CAS RN: 142880-36-2 | Product Number: I1202
Ilomastat
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Purity: >95.0%(HPLC)(qNMR)
Synonyms:
- GM 6001
- Galardin
- (R)-N1-[(S)-3-(1H-Indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-N4-hydroxy-2-isobutylsuccinamide
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 10MG |
£161.00
|
Contact Us | Contact Us |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | I1202 |
| Purity / Analysis Method | >95.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__2__0H__2__8N__4O__4 = 388.47 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 142880-36-2 |
| Reaxys Registry Number | 7982373 |
| MDL Number | MFCD00917040 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
| HS Number | 2933998090 |
Application
lomastat: A Potent And Broad Spectrum Matrix Metalloprotease (MMP) Inhibitor
Matrix metalloproteases (MMPs) are metalloproteinases that are calcium-dependent zinc-containing endopeptidases. MMPs have been reported to play a key role in the degradation and remodeling of the extracellular matrix in various inflammatory diseases. Ilomastat (GM 6001) is a potent and broad-spectrum inhibitor of MMPs. (The product is for research purpose only.)
References
- Inhibition of angiogenesis by the matrix metalloprotease inhibitor N-[2R-2-(hydroxamidocarbonylmethyl)-4-(methylpentanoyl)]-L-tryptophan methylamide
- Improved gelatinase a selectivity by novel zinc binding groups containing galardin derivatives
- Neutrophil Infiltration and Matrix Metalloproteinase-9 in Lacunar Infarction (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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