Published TCIMAIL newest issue No.197
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CAS RN: 18865-38-8 | Product Number: G0579
Glycinexylidide
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Purity: >98.0%(HPLC)
Synonyms:
- 2-Amino-N-(2,6-dimethylphenyl)acetamide
- N-(2,6-Dimethylphenyl)glycinamide
- N-Glycyl-2,6-xylidine
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 50MG |
£46.00
|
1 | 10 |
|
| 250MG |
£158.00
|
Contact Us | 17 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | G0579 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__4N__2O = 178.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 18865-38-8 |
| Reaxys Registry Number | 2416240 |
| PubChem Substance ID | 468591946 |
| MDL Number | MFCD05267700 |
Specifications
| Appearance | White to Light yellow powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 89.0 to 93.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 92 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| HS Number | 2924297099 |
Application
Glycinexylidide: An Active Metabolite of Lidocaine
Glycinexylidide is an active metabolite of lidocaine [L0156] which is metabolized in the liver into two active compounds, glycinexylidide and monoethylglycinexylidide [N1171]. The major metabolic pathway, sequential N-deethylation to them, is primarily mediated by CYP1A2. Therefore, glycinexylidide has been used to assess liver function. (The product is for research purpose only.)
References
- Cytochrome P450 1A2 is a major determinant of lidocaine metabolism in vivo: effects of liver function
- High-performance liquid chromatography-tandem electrospray mass spectrometry for the determination of lidocaine and its metabolites in human plasma and urine
Product Documents (Note: Some products will not have analytical charts available.)
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