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CAS RN: 624-49-7 | Product Number: F0069
Dimethyl Fumarate
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Purity: >98.0%(GC)
Synonyms:
- Fumaric Acid Dimethyl Ester
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25G |
£17.00
|
4 | 5 |
|
| 500G |
£106.00
|
3 | 15 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | F0069 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__6H__8O__4 = 144.13 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 624-49-7 |
| Reaxys Registry Number | 774590 |
| PubChem Substance ID | 87569871 |
| SDBS (AIST Spectral DB) | 1132 |
| Merck Index (14) | 4287 |
| MDL Number | MFCD00064438 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 103.0 to 105.0 °C |
Properties (reference)
| Melting Point | 104 °C |
| Boiling Point | 205 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Acetone, Chloroform |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H312 : Harmful in contact with skin. H315 : Causes skin irritation. H318 : Causes serious eye damage. H317 : May cause an allergic skin reaction. |
| Precautionary Statements | P261 : Avoid breathing dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. |
Related Laws:
| EC Number | 210-849-0 |
| RTECS# | EM6125000 |
Transport Information:
| HS Number | 2917198090 |
Application
Dimethyl Fumarate, An Immunomodulator without Significant Immunosuppression
Recently, the effects of dimethyl fumarate on neuroprotection and immunomodulation have reported. Dimethyl fumarate is thought to have immunomodulatory properties without significant immunosuppression. (The product is for research purpose only.)
References
- The antipsoriatic agent dimethylfumarate immunomodulates T-cell cytokine secretion and inhibits cytokines of the psoriatic cytokine network
- Dimethylfumarate is a potent inducer of apoptosis in human T cells
- Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration
- Dimethylfumarate Induces Immunosuppression via Glutathione Depletion and Subsequent Induction of Heme Oxygenase 1
- Dimethyl fumarate for multiple sclerosis
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