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Published TCIMAIL newest issue No.197
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CAS RN: 120-08-1 | Product Number: D6201
Scoparone
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Purity: >98.0%(GC)
Synonyms:
- 6,7-Dimethoxycoumarin
- 6,7-Dimethylesculetin
- 6,7-Dimethoxy-2H-chromen-2-one
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 250MG |
£109.00
|
Contact Us | ≥60 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D6201 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__1H__1__0O__4 = 206.20 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 120-08-1 |
| Reaxys Registry Number | 169572 |
| MDL Number | MFCD00006871 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 142.0 to 146.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 143 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. |
Related Laws:
| EC Number | 204-369-0 |
| RTECS# | GN6550000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
Application
Scoparone: A Bioactive Coumarin with Anti-Inflammatory and Antioxidant Activities
Scoparone is a coumarin found in Artemisia capillaris Thunberg, which is used in a traditional Chinese herbal medicine called Yīn-Chén-Hāo decoction (YCHD).1) Scoparone has been reported to have anti-inflammatory, antioxidant, anti-apoptotic, anti-fibrotic, and anti-tumor activities.2-4) (The product is for research purpose only.)
References
- 1) Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases (a review)
- 2) Scoparone as a therapeutic drug in liver diseases: Pharmacology, pharmacokinetics and molecular mechanisms of action (a review)
- 3) Scoparone exerts anti-tumor activity against DU145 prostate cancer cells via inhibition of STAT3 activity
- 4) Pharmacokinetics and tissue distribution study of scoparone in rats by ultraperformance liquid-chromatography with tandem high-definition mass spectrometry
Product Documents (Note: Some products will not have analytical charts available.)
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