Published TCIMAIL newest issue No.196
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CAS RN: 73536-69-3 | Product Number: B6112
Bifendate
Purity: >98.0%(GC)
Synonyms:
- Dimethyl 4,4'-Dimethoxy-5,6,5',6'-di(methylenedioxy)biphenyl-2,2'-dicarboxylate
- 4,4'-Dimethoxy-5,6,5',6'-di(methylenedioxy)biphenyl-2,2'-dicarboxylic Acid Dimethyl Ester
Product Documents:
Size | Unit Price | Belgium | Japan* | Quantity |
---|---|---|---|---|
5G |
£34.00
|
1 | 3 |
|
25G |
£113.00
|
Contact Us | 11 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Product Number | B6112 |
Purity / Analysis Method | >98.0%(GC) |
Molecular Formula / Molecular Weight | C__2__0H__1__8O__1__0 = 418.35 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Air Sensitive,Heat Sensitive |
CAS RN | 73536-69-3 |
Reaxys Registry Number | 5461320 |
PubChem Substance ID | 468590917 |
MDL Number | MFCD01751431 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(GC) | min. 98.0 % |
Melting point | 179.0 to 183.0 °C |
NMR | confirm to structure |
Properties (reference)
Melting Point | 181 °C |
Maximum Absorption Wavelength | 276(MeOH) nm |
GHS
Related Laws:
RTECS# | DT4315000 |
Transport Information:
HS Number | 2932990090 |
Application
Bifendate (DDB): A Chemical Synthetic Intermediate of a Constituent of Schizandra sp.
Bifendate (dimethyl diphenyl bicarboxylate: DDB) is a chemical synthetic intermediate of schisandrin C, a constituent of Schizandra sp. which have been used in traditional Chinese medicine as a tonic and sedative.1,2) At present, DDB is widely used as a hepatoprotective agent and is recently found to possess immunomodulatory, as well as neurobehavioral potential.2-4) (The product is for research purpose only.)
References
- 1) Bioactivity of neolignans from fructus Schizandrae (a review)
- 2) Differential effect of schisandrin B and dimethyl diphenyl bicarboxylate (DDB) on hepatic mitochondrial glutathione redox status in carbon tetrachloride intoxicated mice
- 3) The effect of dimethyl dimethoxy biphenyl dicarboxylate (DDB) against tamoxifen-induced liver injury in rats: DDB use is curative or protective
- 4) Effect of biphenyl dimethyl dicarboxylate and fluoxetine on performance of normally-fed and protein malnourished psychologically stressed mice in elevated plus maze
- 5)A simple HPLC method for the determination of bifendate: Application to a pharmacokinetic study of bifendate liposome
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