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Published TCIMAIL newest issue No.197
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CAS RN: 1715-30-6 | Product Number: A3389
Alexidine Dihydrochloride
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Purity: >98.0%(HPLC)(N)
Synonyms:
- 1,1'-Hexamethylenebis[5-(2-ethylhex-1-yl)]biguanide Dihydrochloride
- N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide Dihydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
£38.00
|
Contact Us | 26 |
|
| 100MG |
£91.00
|
1 | 23 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A3389 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__6H__5__6N__1__0·2HCl = 581.72 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1715-30-6 |
| Reaxys Registry Number | 5698790 |
| PubChem Substance ID | 468590270 |
| MDL Number | MFCD00082369 |
Specifications
| Appearance | White to Almost white powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 223.0 to 227.0 °C |
Properties (reference)
| Melting Point | 225 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 216-994-6 |
Transport Information:
| HS Number | 2925290090 |
Application
Alexidine Dihydrochloride: A Cationic Bis(Biguanide) Antimicrobial Agent
Alexidine dihydrochloride is a cationic bis(biguanide) antimicrobial agent. It has been reported that alexidine binds to lipopolysaccharide and lipoteichoic acid and prevents microbial cell activation.1,2) In addition, alexidine induces apoptosis in cancer cell line, and inhibits the protein tyrosine phosphatase mitochondrion-1 (PTPM1).3,4) (The product is for research purpose only.)
References
- 1) Alexidine and chlorhexidine bind to lipopolysaccharide and lipoteichoic acid and prevent cell activation by antibiotics
- 2) Alexidine dihydrochloride has broad-spectrum Activities against diverse fungal pathogens
- 3) Potential use of alexidine dihydrochloride as an apoptosis-promoting anticancer agent
- 4) Pharmacological Targeting of the Mitochondrial Phosphatase PTPMT1
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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