Maintenance Notice (5:30 AM - 12:00 PM December 21, 2024): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.197
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 51-55-8 | Product Number: A0754
Atropine
×
![]()
×
Purity: >99.0%(T)
Synonyms:
- (±)-Hyoscyamine
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
£76.00
|
3 | 34 |
|
| 25G |
£378.00
|
3 | 25 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A0754 |
| Purity / Analysis Method | >99.0%(T) |
| Molecular Formula / Molecular Weight | C__1__7H__2__3NO__3 = 289.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive |
| CAS RN | 51-55-8 |
| Reaxys Registry Number | 91256 |
| PubChem Substance ID | 87562295 |
| SDBS (AIST Spectral DB) | 7817 |
| Merck Index (14) | 875 |
| MDL Number | MFCD00022622 |
Specifications
| Appearance | White powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 99.0 % |
| Melting point | 114.0 to 118.0 °C |
| Solubility in Methanol | almost transparency |
Properties (reference)
| Melting Point | 116 °C |
| Degree of solubility in water | 2.2 g/l 25 °C |
| Solubility (soluble in) | Methanol, Benzene |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 + H330 : Fatal if swallowed or if inhaled. |
| Precautionary Statements | P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P264 : Wash skin thoroughly after handling. P284 : Wear respiratory protection. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. |
Related Laws:
| EC Number | 200-104-8 |
| RTECS# | CK0700000 |
Transport Information:
| UN Number | UN1544 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2939799090 |
Application
Atropine: A Nonselective Muscarinic Acetylcholinergic Receptors Antagonist
Atropine, a tropane alkaloid, is a free base of its sulfate [A0550] which was first extracted from the root of belladonna (Atropa belladonna) in 1830s. Atropine is a enantiomeric mixture of (R,S)-hyoscyamine (dl-hyoscyamine), racemization occurring during the extraction procedure, whereas only (S)-hyoscyamine (l-hyoscyamine) [H0450] is the active isomer. Atropine is a competitive antagonist of muscarine-like actions of acetylcholine and is therefore classified as an antimuscarinic agent. Atropine does not distinguish among the M1, M2, and M3 subgroups of muscarinic receptors. Atropine inhibits the action of acetylcholine at postganglionic nerve endings, thus affecting receptors of the exocrine glands, smooth muscle, cardiac muscle and the central nervous system. (The product is for research purpose only.)
References
- Muscarinic antagonists in development for disorders of smooth muscle function (a review)
- Atropine (a review on the chemical and physical properties, isolation, synthesis, methods of analysis, and pharmacology of atropine)
- High-performance liquid chromatographic determination of atropine and atropine-like alkaloids in pharmaceutical preparations with indirect conductometric detection
- Determination of atropine in pharmaceutical preparations by liquid chromatography with fluorescence detection
- Analysis of atropine, its degradation products and related substances of natural origin by means of reversed-phase high-performance liquid chromatography
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.