Maintenance Notice (4:30 AM - 11:00 AM December 21, 2024): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.197
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 4143-62-8 | Product Number: D4794
3',4'-Dimethoxyflavone
×
![]()
×
Purity: >98.0%(GC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
55,00 €
|
1 | 5 |
|
| 1G |
193,00 €
|
1 | 20 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D4794 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__4O__4 = 282.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 4143-62-8 |
| Reaxys Registry Number | 236749 |
| PubChem Substance ID | 354333484 |
| MDL Number | MFCD00143009 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 151.0 to 155.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 153 °C |
| Maximum Absorption Wavelength | 334(MeOH) nm |
GHS
Related Laws:
| RTECS# | DJ3012950 |
Transport Information:
| HS Number | 2932990090 |
Application
3',4'-Dimethoxyflavone: An Inhibitor of Poly (ADP-Ribose) Polymerase (PARP) Enzymes
Genomic instability is a hallmark of cancer and is often the result of altered DNA repair capabilities in tumor cells. Poly (ADP-ribose) polymerases (PARPs) are enzymes responsible for DNA damage detection and repair factor recruitment. PARP inhibitors are able to interact with the binding site for the PARP cofactor NAD+ and trap PARP on DNA, and induce cell death through replication stress-induced mitotic catastrophe. It has been reported that 3',4'-dimethoxyflavone is a PARP inhibitor and has neuroprotective effects. (The product is for research use only.)
Reference
- Identification through high-throughput screening of 4'-methoxyflavone and 3',4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatos
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.