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CAS RN: 155-41-9 | Product Number: S0231
Scopolamine Methyl Bromide
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Methscopolamine Bromide
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€52.00
|
1 | 34 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | S0231 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__4BrNO__4 = 398.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 155-41-9 |
| Related CAS RN | 13265-10-6 |
| Reaxys Registry Number | 4079680 |
| PubChem Substance ID | 87575768 |
| Merck Index (14) | 6003 |
| MDL Number | MFCD00078560 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | -23.0 to -26.0 deg(C=1, H2O) |
Properties (reference)
| Specific Rotation | -24° (C=1,H2O) |
GHS
Related Laws:
| EC Number | 205-844-5 |
| RTECS# | YM3675000 |
Transport Information:
| UN Number | UN1544 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2939799090 |
Application
Scopolamine Methyl Bromide: A Belladonna Alkaloid with Anticholinergic Activity
Scopolamine salts ([S0021][S0230] and [S0231]), belladonna alkaloids, are anticholinergic agents. Their free base, scopolamine competitively inhibits muscarinic receptors of the parasympathetic nervous system for acetylcholine and act as a nonselective muscarinic antagonist, producing peripheral anti-muscarinic, central sedative and antiemetic effects. The parasympatholytic scopolamine, structurally very similar to atropine [A0754] as well, is used in conditions requiring decreased parasympathetic activity. Therefore, scopolamine can inhibit the secretion of saliva and sweat, decrease gastrointestinal secretions and motility, and increase heart rate et al. (The product is for research purpose only.)
References
- Effects of scopolamine and methylscopolamine on classical conditioning of the rabbit nictitating membrane response
- Effects of cholinergic and monoaminergic antagonists and tranquilizers upon spatial memory in rats
- Effects of physostigmine and scopolamine in rats' performances in object-recognition and radial-maze tests
- Scanning mutagenesis studies of the M1 muscarinic acetylcholine receptor
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