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Published TCIMAIL newest issue No.197
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CAS RN: 148-72-1 | Product Number: P0399
Pilocarpine Nitrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
€246.00
|
1 | 17 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | P0399 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__1H__1__6N__2O__2·HNO__3 = 271.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 148-72-1 |
| Reaxys Registry Number | 6553906 |
| PubChem Substance ID | 87574606 |
| Merck Index (14) | 7424 |
| MDL Number | MFCD00078497 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +80.0 to +84.0 deg(C=2, H2O) |
| Solubility in Water | almost transparency |
Properties (reference)
| Melting Point | 171 °C |
| Specific Rotation | 81° (C=2,H2O) |
| Solubility in water | Soluble |
| Solubility (insoluble in) | Chloroform |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H330 : Fatal if inhaled. H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P260 : Do not breathe dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P284 : Wear respiratory protection. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. |
Related Laws:
| EC Number | 205-723-7 |
| RTECS# | TK1455000 |
Transport Information:
| HS Number | 2939799090 |
Application
Pilocarpine Nitrate: A Muscarinic Acetylcholine Receptor Agonist
Pilocarpine is an imidazole alkaloid contained in the leaves of Pilocarpus jaborandi and Pilocarpus microphyllus distributed throughout South America. It is a direct acting cholinergic parasympathomimetic agent which acts through direct stimulation of muscarinic acetylcholine receptors (M1, M2, and M3) with low affinity for nicotine receptors. (The product is for research purpose only.)
References
- Human M1-, M2- and M3-muscarinic cholinergic receptors: Binding characteristics of agonists and antagonists
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