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CAS RN: 167933-07-5 | Product Number: F1239
Flibanserin
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Purity: >97.0%(T)(HPLC)
Synonyms:
- 1-[2-[4-[3-(Trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1,3-dihydro-2H-benzo[d]imidazol-2-one
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€82.00
|
1 | 22 |
|
| 100MG |
€204.00
|
Contact Us | 30 |
|
| 500MG |
€692.00
|
Contact Us | 29 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | F1239 |
| Purity / Analysis Method | >97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__1F__3N__4O = 390.41 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 167933-07-5 |
| Reaxys Registry Number | 8942243 |
| PubChem Substance ID | 468591871 |
| MDL Number | MFCD00918402 |
Specifications
| Appearance | White to Almost white powder to crystaline |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 161.0 to 165.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 163 °C |
| Solubility in water | Insoluble |
| Degree of solubility in water | 4.312 mg/l 25 °C |
| Solubility (soluble in) | Acetone |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | DE2557500 |
Transport Information:
| HS Number | 2933599590 |
Application
Flibanserin: A Multimodal Serotonergic Agent
Flibanserin is a multimodal serotonergic agent that has a preferential affinity for serotonin 5-HT1A, dopamine D4, and serotonin 5-HT2A receptors. In vitro studies has suggested that flibanserin acts as a 5-HT1A agonist, a very weak partial agonist on dopamine D4 receptors, and 5-HT2A antagonist. And then, flibanserin is believed to show antipsychotic effects by increasing levels of dopamine and noradrenaline and lowering levels of serotonin in the brain. (The product is for research purpose only.)
References
- Pharmacology of flibanserin (a review)
- Multifunctional pharmacology of flibanserin: possible mechanism of therapeutic action in hypoactive sexual desire disorder (a review)
- Flibanserin: First Global Approval (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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