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CAS RN: 4956-37-0 | Product Number: E1151
β-Estradiol 17-Heptanoate
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Purity: >98.0%(GC)
Synonyms:
- β-Estradiol 17-Enanthate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€67.00
|
1 | Contact Us |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | E1151 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__5H__3__6O__3 = 384.56 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 4956-37-0 |
| Reaxys Registry Number | 3166479 |
| PubChem Substance ID | 253660905 |
| Merck Index (14) | 3703 |
| MDL Number | MFCD00056542 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 107.0 to 111.0 °C |
| Specific rotation [a]20/D | +42.0 to +46.0 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 109 °C |
| Specific Rotation | 44° (C=1,CHCl3) |
| Maximum Absorption Wavelength | 286(EtOH) nm |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| EC Number | 225-599-8 |
Transport Information:
| HS Number | 2937230000 |
Application
β-Estradiol 17-Heptanoate: A Long-Acting Fatty Acid Ester of β-Estradiol
Free β-estradiol [E0025] is the primary female sex hormone, an estrogen. β-Estradiol 17-heptanoate, a synthetic fatty acid esters, is a long-acting β-estradiol. Compared with free β-estradiol, β-estradiol fatty acid esters are metabolized more slowly and thereby have more potent estrogenic properties. In theory, β-estradiol fatty acid esters could function as a storage form of estradiol in tissues and be hydrolyzed to free hormone when needed.
References
- Synthesis and biological assessment of long-acting estradiol fatty acid esters in ovariectomized rats
- Long-term permeation kinetics of estradiol: III. Kinetic analyses of the simultaneous skin permeation and bioconversion of estradiol esters
- Long-acting estrogenic responses of estradiol fatty acid esters
- Quantitative determination of estradiol fatty acid esters in human pregnancy serum and ovarian follicular fluid
- Ultra high performance liquid chromatography/tandem mass spectrometry based identification of steroid esters in serum and plasma: An efficient strategy to detect natural steroids abuse in breeding and racing animals
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